Dr. Cheng Luo's Logbook

  Dr. Cheng Luo (born October 26, 1958), Porvoo, Finland,  Professor in Food Science (Zhejiang Ocean University, Tianjin University of Science and Technology, Senior Research Scientist in virology and medical science (Turku University and Tartu University), Ph. D, Helsinki University, 1993, | World Biographical Encyclopedia (prabook.com) A Chinese/Finnish scientist, Sichuan University (1978-1982, Chengdu, China), resaech assistant in baceriophages (Vienna University,1988-1989), virus structure (Helsinki U 1989-1993), plant physiology (Umeå U 1996-1998), medicine (Turku U 1998-2003) COX-2 in pancreatic beta-cells. Recipient for traveling support to Hawaii, USA for COX-2 (inhibitor) workshop, Pfizer, 1999, Wang K. Edu. Foundation, Hong Kong, China, 2000. OMRF, USA 2003-04, HKU 2005-2007, Biotechnology: Senior Scientist Tartu U. 2008-2015, Food Sci. Professor Tianjin U 2010-2014, Zhejiang Ocean U 2016-2020. Current interests: 1, GDNF gene network to artificial neural network Some thoughts

  Dear Prof. Tomas Kubicek, It was very nice to meet you in your library (www.mzk.cz) in Brno, Czech Republic on August 31, 2022. It was very interesting to listen to you to introduce Mr. Milan Kundera, a world-famous Czeck born philosopher writer. Actually, one of my classmates who live in Canada, and another young Chinese lady who currentl live in China, have read “The Unbearable Lightness of Being”, and my wife also watched the movie directed by Philip Kaufman. They commented it was because of similar history with China, the vogue and foggy expectation, and the love story, respectively. I think the background of Mr. Milan Kundera’s novel was clear for all three commentators, but their own life experience very much geographically different. Probably Milan Kundera has been good luck (maybe wrong expression) because I found that his work was recognized quite early, for instance, he got Jerusalem Prize for Literature in 1985 already. Of course, that is because his work brought many new

https://lponet.fi/omat-palveluni

 

 

 

  Verbascoside inhibits cell proliferation, migration, and invasion of oral squamous cell carcinoma by the METTL3-mediated miR-31-5p/HIPK2 axis     根据 << 手稿审查批注 / 修改意见工作指南 >> 里的 7 点，都基本上 OK ， 文章没有逻辑上，数据上显而易见的缺陷和不足， 但文章没有亮点，没有创新 , 作者缺乏药物筛选方面的专业考虑（当然不是药物筛选文章）。   研究的方法 / 实验设计基本合理，方法和实验过程基本恰当，虽然 整个思路在 METTL3/ miR-31-5p/HIPK2 信号上分析的差异没有冲突，也观察到合理的变化。 但已经有相似报道。   结果及结论基本 OK: Fig. 2, 4, 7 图解需要更清晰： Fluorescence images of anti-BrdU assay of cell division and proliferation after compound treatment.   transwell 的图片质量都不好， 主要是显微镜没有聚焦好， 计数可能会带来偏差   EDU assay 中 可能 20M 浓度太高， 导致 520 nm 反射光（红）太强， 以致完全覆盖 DAPI （ green ）染色， 这可能导致计数误差。   标题与摘要基本 OK( 但需要修改 ) ，毛蕊花苷购买于成都，但必须有公司名，甚至批次。 作为严格的剂量测试， 应该还缺一个 ( 更高的 ) 剂量， 现在看不到这个分子是否是剂量依赖性 ? 还是非剂量依赖型。     当然需要 伦理批文号，   讨论部分需要补充。经过专业修改后，可以突出主要发现，提高文章分量及阅读兴趣」当然还有很多细节需要通过 peer review 改进。   参考文献引用基本合理；文章整体结构、语言语法等基本 Ok, 图表漂亮、   很多缩写没有全称如 RIP (RNA immunoprecipitation), MeRIP (methylated RIP)   整个工作背景不够详细，比如 M6A

  ANTXR1 Regulates Erythroid Cell Proliferation and Differentiation through wnt/ β-Catenin Signaling Pathway In Vitro and in Hematopoietic Stem Cell - PubMed (nih.gov) Interleukin-17A influences the vulnerability rather than the size of established atherosclerotic plaques in apolipoprotein E-deficient mice (degruyter.com) Molecular Mechanism of Traditional Chinese Ointment of Xuzhou Qufu Shengji in Infected Wounds (hindawi.com) Transmembrane Protein ANTXR1 Regulates γ-Globin Expression by Targeting the Wnt/ β-Catenin Signaling Pathway - PubMed (nih.gov) Influences of advanced glycosylation end products on the inner blood-retinal barrier in a co-culture cell model in vitro - PubMed (nih.gov)

 

  Czech Writer Gets Jerusalem Literary Prize | AP News Czech Writer Gets Jerusalem Literary Prize May 10, 1985 JERUSALEM (AP) _ Exiled Czechoslovakian novelist Milan Kundera, whose books were banned in his homeland, has been awarded the Jerusalem Prize for the Freedom of Man in Society by Mayor Teddy Kollek. The $5,000 prize was presented to Kundera on Wednesday night in conjunction with Israel’s annual book fair. The three-member judging panel said Kundera had ″given expression to the struggle of the individual for his freedom and uniqueness against the forces of history, regime and politics.″ Kundera, 56, has been living in Paris and lecturing at French universities since 1975. The Czechoslovakian government abrogated his citizenship in 1979. He was expelled from the Communist Party in 1969 for what the authorities called ″ideological deviations″ and his books were banned. The panel said Kundera’s ″exile and his neutrality from defined political identification enable him to observe b